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Studies were included if they investigated mtROS-related mechanisms in skeletal muscle, addressed muscle atrophy or disuse with relevance to mitochondrial function, or examined rotator cuff injury-associated supraspinatus pathology

Disruption of PKA signaling is linked to altered fat and glucose metabolism in obesity

While the correlation is not perfect, peripheral blood BDNF serves as a reasonable proxy for central nervous system BDNF status

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